AGTRAP

AGTRAP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZV0, 4YAY
Identifiers
Aliases	AGTRAP, ATRAP, angiotensin II receptor associated protein
External IDs	OMIM: 608729; MGI: 1339977; HomoloGene: 7621; GeneCards: AGTRAP; OMA:AGTRAP - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	11,754,802 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	148,172,488 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; right uterine tube; ; pancreatic ductal cell; ; blood; ; gastric mucosa; ; spleen; ; right lung; ; upper lobe of left lung; ; bone marrow;
	Top expressed in
	blastocyst; ; right kidney; ; granulocyte; ; choroid plexus of fourth ventricle; ; proximal tubule; ; gastrula; ; Ileal epithelium; ; yolk sac; ; human kidney; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; angiotensin type II receptor activity;
Cellular component	integral component of membrane; Golgi membrane; plasma membrane; Golgi apparatus; cell cortex; endoplasmic reticulum membrane; cytoplasmic vesicle membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; membrane; cytoplasmic vesicle; nucleoplasm; cytosol;
Biological process	regulation of blood pressure; angiotensin-activated signaling pathway; response to hypoxia;
	Sources:Amigo / QuickGO
Orthologs
	57085
	11610
	ENSG00000177674
	ENSMUSG00000029007
	Q6RW13
	Q9WVK0
	NM_001040194; NM_001040195; NM_001040196; NM_001040197; NM_020350
	NM_001301281; NM_009642
	NP_001035284; NP_001035285; NP_001035286; NP_001035287; NP_065083
	NP_001288210; NP_033772
	Wikidata
View/Edit Human	View/Edit Mouse

Type-1 angiotensin II receptor-associated protein is a protein that in humans is encoded by the AGTRAP gene.

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.