AHNAK

AHNAK
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	4DRW, 4FTG, 4HRG
Identifiers
Aliases	AHNAK, AHNAKRS, AHNAK nucleoprotein, PM227
External IDs	OMIM: 103390; MGI: 1316648; HomoloGene: 67425; GeneCards: AHNAK; OMA:AHNAK - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	62,556,235 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	9,054,278 bp
RNA expression pattern
	Top expressed in
	olfactory bulb; ; Achilles tendon; ; tendon of biceps brachii; ; trigeminal ganglion; ; saphenous vein; ; mucosa of pharynx; ; nipple; ; epithelium of colon; ; urethra; ; skin of hip;
	Top expressed in
	sciatic nerve; ; ascending aorta; ; corneal stroma; ; aortic valve; ; gastrula; ; skin of external ear; ; right lung lobe; ; conjunctival fornix; ; endothelial cell of lymphatic vessel; ; tunica media of zone of aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	S100 protein binding; structural molecule activity conferring elasticity; protein binding; RNA binding; cadherin binding;
Cellular component	cytoplasm; vesicle; cytosol; membrane; cell-cell contact zone; focal adhesion; plasma membrane; lysosomal membrane; actin cytoskeleton; membrane raft; sarcolemma; costamere; extracellular exosome; nucleus; T-tubule;
Biological process	regulation of voltage-gated calcium channel activity; regulation of RNA splicing; protein complex oligomerization;
	Sources:Amigo / QuickGO
Orthologs
	79026
	66395
	ENSG00000124942
	ENSMUSG00000069833
	Q09666
	n/a
	NM_001620; NM_024060; NM_001346445; NM_001346446
	NM_001039959; NM_001286518; NM_009643; NM_175108
	NP_001333374; NP_001333375; NP_001611; NP_076965
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Neuroblast differentiation-associated protein AHNAK, also known as desmoyokin, is a protein that in humans is encoded by the AHNAK gene. AHNAK was originally identified in 1989 (in bovine muzzle epidermal cells) and named desmoyokin due to its localization pattern (that resembled a yoke) in the desmosomal plaque. AHNAK has been shown to be essential for pseudopod protrusion and cell migration.