AKAP12

AKAP12
Identifiers
Aliases	AKAP12, AKAP250, SSeCKS, A-kinase anchoring protein 12
External IDs	OMIM: 604698; MGI: 1932576; HomoloGene: 3740; GeneCards: AKAP12; OMA:AKAP12 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	151,358,559 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	4,309,470 bp
RNA expression pattern
	Top expressed in
	Pons; ; lateral nuclear group of thalamus; ; spinal ganglia; ; trigeminal ganglion; ; vena cava; ; pars compacta; ; saphenous vein; ; superior vestibular nucleus; ; pericardium; ; epithelium of colon;
	Top expressed in
	efferent ductule; ; seminiferous tubule; ; vas deferens; ; stroma of bone marrow; ; external carotid artery; ; left lung lobe; ; spermatid; ; superior cervical ganglion; ; endothelial cell of lymphatic vessel; ; dermis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase A binding; protein binding; adenylate cyclase binding;
Cellular component	plasma membrane; cell cortex; cytoskeleton; membrane; focal adhesion; cytoplasm; cytosol; Schaffer collateral - CA1 synapse; soma;
Biological process	protein targeting; G protein-coupled receptor signaling pathway; regulation of protein kinase C signaling; signal transduction; positive regulation of protein kinase A signaling; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; regulation of protein kinase A signaling; modulation of chemical synaptic transmission; response to lipopolysaccharide; hepatic stellate cell activation; negative regulation of vascular permeability; response to electrical stimulus; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of hepatic stellate cell migration; positive regulation of ERK1 and ERK2 cascade; cellular response to interleukin-1; cellular response to tumor necrosis factor; positive regulation of oligodendrocyte apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	9590
	83397
	ENSG00000131016
	ENSMUSG00000038587
	Q02952
	Q9WTQ5
	NM_005100; NM_144497; NM_001370346
	NM_031185
	NP_005091; NP_653080; NP_001357275
	NP_112462
	Wikidata
View/Edit Human	View/Edit Mouse

A-kinase anchor protein 12, aka AKAP250, is an enzyme that in humans is encoded by the AKAP12 gene.