AKAP8

AKAP8
Identifiers
Aliases	AKAP8, AKAP 95, AKAP-8, AKAP-95, AKAP95, A-kinase anchoring protein 8
External IDs	OMIM: 604692; MGI: 1928488; HomoloGene: 4278; GeneCards: AKAP8; OMA:AKAP8 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	15,379,815 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	32,540,212 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; granulocyte; ; right uterine tube; ; Achilles tendon; ; gastrocnemius muscle; ; gastric mucosa; ; left uterine tube; ; spleen; ; body of uterus; ; skin of leg;
	Top expressed in
	neural layer of retina; ; tail of embryo; ; otic vesicle; ; genital tubercle; ; otic placode; ; ventricular zone; ; cerebellar cortex; ; epiblast; ; cumulus cell; ; saccule;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; DNA binding; zinc ion binding; double-stranded DNA binding; protein kinase A regulatory subunit binding; histone deacetylase binding; DEAD/H-box RNA helicase binding; protein binding; NF-kappaB binding; RNA binding;
Cellular component	Golgi apparatus; female pronucleus; membrane; condensed chromosome; nucleus; mitochondrion; nucleoplasm; nucleolus; nuclear matrix; cytoplasm;
Biological process	positive regulation of histone deacetylation; mitotic chromosome condensation; signal transduction; cell cycle G2/M phase transition; regulation of transcription, DNA-templated; immune system process; cellular response to lipopolysaccharide; cellular response to prostaglandin E stimulus; transcription, DNA-templated; protein transport; negative regulation of tumor necrosis factor production; innate immune response; mitotic cell cycle; transport;
	Sources:Amigo / QuickGO
Orthologs
	10270
	56399
	ENSG00000105127
	ENSMUSG00000024045
	O43823
	Q9DBR0
	NM_005858
	NM_019774; NM_001357760
	NP_005849
	NP_062748; NP_001344689
	Wikidata
View/Edit Human	View/Edit Mouse

A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.