Protein kinase B
| AKT1 | |||||||
|---|---|---|---|---|---|---|---|
Ribbon Representation of crystal structure of Akt-1-inhibitor complexes. | |||||||
| Identifiers | |||||||
| Symbol | AKT1 | ||||||
| NCBI gene | 207 | ||||||
| HGNC | 391 | ||||||
| OMIM | 164730 | ||||||
| RefSeq | NM_005163 | ||||||
| UniProt | P31749 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q32.32-32.33 | ||||||
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| AKT2 | |||||||
|---|---|---|---|---|---|---|---|
Crystal structure of Akt-2-inhibitor complexes. | |||||||
| Identifiers | |||||||
| Symbol | AKT2 | ||||||
| NCBI gene | 208 | ||||||
| HGNC | 392 | ||||||
| OMIM | 164731 | ||||||
| RefSeq | NM_001626 | ||||||
| UniProt | P31751 | ||||||
| Other data | |||||||
| Locus | Chr. 19 q13.1-13.2 | ||||||
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| AKT3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | AKT3 | ||||||
| NCBI gene | 10000 | ||||||
| HGNC | 393 | ||||||
| OMIM | 611223 | ||||||
| RefSeq | NM_181690 | ||||||
| UniProt | Q9Y243 | ||||||
| Other data | |||||||
| Locus | Chr. 1 q43-44 | ||||||
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Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.