ALDH1A1

ALDH1A1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WB9, 4WJ9, 4WP7, 4WPN, 4X4L, 5AC2
Identifiers
Aliases	ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1, aldehyde dehydrogenase 1 family member A1
External IDs	OMIM: 100640; MGI: 1353450; HomoloGene: 110441; GeneCards: ALDH1A1; OMA:ALDH1A1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	73,080,442 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	20,643,462 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; nasal epithelium; ; mucosa of paranasal sinus; ; islet of Langerhans; ; jejunal mucosa; ; olfactory zone of nasal mucosa; ; duodenum; ; corpus epididymis; ; pars reticulata; ; body of pancreas;
	Top expressed in
	right lung lobe; ; epithelium of lens; ; ventral tegmental area; ; left lobe of liver; ; substantia nigra; ; superior surface of tongue; ; gallbladder; ; Gonadal ridge; ; epithelium of stomach; ; ciliary body;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; benzaldehyde dehydrogenase (NAD+) activity; androgen binding; aldehyde dehydrogenase (NAD+) activity; GTPase activator activity; nucleotide binding; retinal dehydrogenase activity; NAD binding; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; extracellular exosome; cytosol;
Biological process	retinol metabolic process; cellular aldehyde metabolic process; metabolism; ethanol oxidation; positive regulation of GTPase activity; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate; retinoid metabolic process; negative regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	216
	11668
	ENSG00000165092
	ENSMUSG00000053279
	P00352
	P24549
	NM_000689
	NM_013467
	NP_000680
	NP_038495; NP_001348432; NP_001348433; NP_001348434; NP_001348435
	Wikidata
View/Edit Human	View/Edit Mouse

Aldehyde dehydrogenase 1 family, member A1, also known as ALDH1A1 or retinaldehyde dehydrogenase 1 (RALDH1), is an enzyme that is encoded by the ALDH1A1 gene.