ALDH1A2

ALDH1A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4X2Q
Identifiers
Aliases	ALDH1A2, RALDH(II), RALDH2, RALDH2-T, aldehyde dehydrogenase 1 family member A2
External IDs	OMIM: 603687; MGI: 107928; HomoloGene: 68368; GeneCards: ALDH1A2; OMA:ALDH1A2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	58,497,866 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	71,203,525 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; decidua; ; sperm; ; seminal vesicula; ; secondary oocyte; ; right uterine tube; ; endometrium; ; parietal pleura; ; tail of epididymis; ; body of uterus;
	Top expressed in
	vas deferens; ; primitive streak; ; vestibular sensory epithelium; ; spermatocyte; ; stria vascularis; ; gastrula; ; optic nerve; ; uterus; ; genital tubercle; ; seminiferous tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; aldehyde dehydrogenase (NAD+) activity; retinal binding; retinal dehydrogenase activity; 3-chloroallyl aldehyde dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; cytosol; perinuclear region of cytoplasm;
Biological process	cellular response to retinoic acid; proximal/distal pattern formation; response to cytokine; pituitary gland development; response to estradiol; 9-cis-retinoic acid biosynthetic process; neural crest cell development; cardiac muscle tissue development; lung development; kidney development; retinol metabolic process; heart morphogenesis; hindbrain development; retinoic acid metabolic process; retinal metabolic process; embryonic camera-type eye development; retinoic acid biosynthetic process; response to vitamin A; face development; positive regulation of gene expression; retinoic acid receptor signaling pathway; blood vessel development; embryonic limb morphogenesis; ureter maturation; neural tube development; neuron differentiation; positive regulation of cell population proliferation; regulation of endothelial cell proliferation; positive regulation of apoptotic process; pancreas development; determination of bilateral symmetry; vitamin A metabolic process; liver development; forebrain development; camera-type eye development; metabolism; morphogenesis of embryonic epithelium; embryonic digestive tract development; embryonic forelimb morphogenesis; anterior/posterior pattern specification; negative regulation of cell population proliferation; midgut development; retinoic acid receptor signaling pathway involved in somitogenesis; protein homotetramerization;
	Sources:Amigo / QuickGO
Orthologs
	8854
	19378
	ENSG00000128918
	ENSMUSG00000013584
	O94788
	Q62148
	NM_170697; NM_001206897; NM_003888; NM_170696
	NM_009022
	NP_001193826; NP_003879; NP_733797; NP_733798
	NP_033048
	Wikidata
View/Edit Human	View/Edit Mouse

Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene.