ALDH1A3

ALDH1A3
Identifiers
Aliases	ALDH1A3, ALDH1A6, ALDH6, MCOP8, RALDH3, aldehyde dehydrogenase 1 family member A3
External IDs	OMIM: 600463; MGI: 1861722; HomoloGene: 68080; GeneCards: ALDH1A3; OMA:ALDH1A3 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	100,916,626 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	66,077,265 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; retinal pigment epithelium; ; parietal pleura; ; parotid gland; ; prostate; ; germinal epithelium; ; periodontal fiber; ; urethra; ; minor salivary glands; ; tail of epididymis;
	Top expressed in
	vestibular sensory epithelium; ; saccule; ; utricle; ; nasal placode; ; corneal stroma; ; conjunctival fornix; ; medullary collecting duct; ; renal pelvis; ; cochlear nerve; ; corneal epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; aldehyde dehydrogenase [NAD(P)+ activity]; NAD+ binding; oxidoreductase activity; aldehyde dehydrogenase (NAD+) activity; thyroid hormone binding; retinal dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; extracellular exosome; nucleus; cytosol; plasma membrane;
Biological process	locomotory behavior; neuromuscular process controlling balance; retinol metabolic process; embryonic eye morphogenesis; nucleus accumbens development; retinoic acid metabolic process; olfactory pit development; retinal metabolic process; face development; inner ear morphogenesis; positive regulation of apoptotic process; optic cup morphogenesis involved in camera-type eye development; metabolism; righting reflex; retinoic acid biosynthetic process; embryonic camera-type eye development; nose development; protein homotetramerization; Harderian gland development;
	Sources:Amigo / QuickGO
Orthologs
	220
	56847
	ENSG00000184254
	ENSMUSG00000015134
	P47895
	Q9JHW9
	NM_001293815; NM_000693; NM_001037224
	NM_053080
	NP_000684; NP_001280744
	NP_444310
	Wikidata
View/Edit Human	View/Edit Mouse

Aldehyde dehydrogenase 1 family, member A3 (ALDH1a3), also known as retinaldehyde dehydrogenase 3 (RALDH3) or as ALDH6 in earlier published studies, is an enzyme that in humans is encoded by the ALDH1A3 gene.,