Long-chain-aldehyde dehydrogenase

ALDH3A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4QGK
Identifiers
Aliases	ALDH3A2, aldehyde dehydrogenase 3 family, member A2, ALDH10, FALDH, SLS, aldehyde dehydrogenase 3 family member A2
External IDs	OMIM: 609523; MGI: 1353452; HomoloGene: 55458; GeneCards: ALDH3A2; OMA:ALDH3A2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	19,685,760 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	61,158,290 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; skin of thigh; ; skin of hip; ; skin of abdomen; ; hair follicle; ; kidney tubule; ; nipple; ; skin of arm;
	Top expressed in
	right kidney; ; left lobe of liver; ; gastrula; ; granulocyte; ; mucous cell of stomach; ; lacrimal gland; ; decidua; ; duodenum; ; yolk sac; ; gallbladder;
	More reference expression data
	n/a
Gene ontology
Molecular function	long-chain-aldehyde dehydrogenase activity; long-chain-alcohol oxidase activity; medium-chain-aldehyde dehydrogenase activity; oxidoreductase activity; aldehyde dehydrogenase (NAD+) activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; protein binding; protein homodimerization activity; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; 3-chloroallyl aldehyde dehydrogenase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; peroxisome; endoplasmic reticulum; peroxisomal membrane; organelle membrane;
Biological process	peripheral nervous system development; sesquiterpenoid metabolic process; phytol metabolic process; sphingolipid biosynthetic process; cellular aldehyde metabolic process; central nervous system development; epidermis development; metabolism; fatty acid alpha-oxidation; hexadecanal metabolic process; lipid metabolism; fatty acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	224
	11671
	ENSG00000072210
	ENSMUSG00000010025
	P51648
	P47740
NM_000382; NM_001031806; NM_001369136; NM_001369137; NM_001369138;
	NM_001369139; NM_001369146; NM_001369148
	NM_007437; NM_001331114; NM_001331115
NP_000373; NP_001026976; NP_001356065; NP_001356066; NP_001356067;
	NP_001356068; NP_001356075; NP_001356077
	NP_001318043; NP_001318044; NP_031463
	Wikidata
View/Edit Human	View/Edit Mouse

Fatty aldehyde dehydrogenase (or long-chain-aldehyde dehydrogenase) is an aldehyde dehydrogenase enzyme that in human is encoded in the ALDH3A2 gene on chromosome 17. Aldehyde dehydrogenase enzymes function to remove toxic aldehydes that are generated by the metabolism of alcohol and by lipid peroxidation.