Aldehyde dehydrogenase 5 family, member A1

ALDH5A1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2W8N, 2W8O, 2W8P, 2W8Q, 2W8R
Identifiers
Aliases	ALDH5A1, SSADH, SSDH, Aldehyde dehydrogenase 5 family, member A1, aldehyde dehydrogenase 5 family member A1
External IDs	OMIM: 610045; MGI: 2441982; HomoloGene: 840; GeneCards: ALDH5A1; OMA:ALDH5A1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	24,537,207 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	25,121,644 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; vastus lateralis muscle; ; liver; ; frontal pole; ; postcentral gyrus; ; Brodmann area 10; ; nucleus accumbens; ; superior frontal gyrus; ; Region I of hippocampus proper; ; paraflocculus of cerebellum;
	Top expressed in
	dorsal tegmental nucleus; ; superior colliculus; ; medial vestibular nucleus; ; central gray substance of midbrain; ; globus pallidus; ; habenula; ; lateral hypothalamus; ; paraventricular nucleus of hypothalamus; ; ventral tegmental area; ; nucleus accumbens;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; oxidoreductase activity; succinate-semialdehyde dehydrogenase (NAD+) activity; succinate-semialdehyde dehydrogenase [NAD(P)+ activity]; NAD binding; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	gamma-aminobutyric acid catabolic process; galactosylceramide metabolic process; glutathione metabolic process; gamma-aminobutyric acid metabolic process; post-embryonic development; short-chain fatty acid metabolic process; neurotransmitter catabolic process; glucosylceramide metabolic process; succinate metabolic process; central nervous system development; glutamine metabolic process; glucose metabolic process; glutamate metabolic process; glycerophospholipid metabolic process; metabolism; respiratory electron transport chain; protein homotetramerization; acetate metabolic process; glutamate decarboxylation to succinate;
	Sources:Amigo / QuickGO
Orthologs
	7915
	214579
	ENSG00000112294
	ENSMUSG00000035936
	P51649
	Q8BWF0
	NM_170740; NM_001080; NM_001368954
	NM_172532
	NP_001071; NP_733936; NP_001355883
	NP_766120
	Wikidata
View/Edit Human	View/Edit Mouse

Succinate-semialdehyde dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ALDH5A1 gene.