ALG14

ALG14
Identifiers
Aliases	ALG14, CMS15, UDP-N-acetylglucosaminyltransferase subunit, ALG14 UDP-N-acetylglucosaminyltransferase subunit, IDDEBF, MEPCA
External IDs	OMIM: 612866; MGI: 1914039; HomoloGene: 49751; GeneCards: ALG14; OMA:ALG14 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	95,072,951 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	121,156,743 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; jejunal mucosa; ; mucosa of colon; ; mucosa of sigmoid colon; ; right adrenal gland; ; oral cavity; ; left adrenal gland; ; caput epididymis; ; Achilles tendon; ; palpebral conjunctiva;
	Top expressed in
	sciatic nerve; ; retinal pigment epithelium; ; vestibular membrane of cochlear duct; ; calvaria; ; otic placode; ; lumbar spinal ganglion; ; morula; ; genital tubercle; ; carotid body; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity;
Cellular component	integral component of membrane; nuclear membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; nucleus; UDP-N-acetylglucosamine transferase complex;
Biological process	dolichol-linked oligosaccharide biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	199857
	66789
	ENSG00000172339
	ENSMUSG00000039887
	Q96F25
	Q9D081
	NM_001305242; NM_144988
	NM_024178
	NP_001292171; NP_659425
	NP_077140
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-N-acetylglucosamine transferase subunit ALG14 homolog is a protein that in humans is encoded by the ALG14 gene.

Asparagine (N)-glycosylation is an essential modification that regulates protein folding and stability. ALG13 and ALG14 (this protein) constitute the UDP-GlcNAc transferase, which catalyzes a key step in endoplasmic reticulum N-linked glycosylation.