Alkaline phosphatase, placental type

ALPP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EW2, 1ZEB, 1ZED, 1ZEF, 2GLQ, 3MK0, 3MK1, 3MK2
Identifiers
Aliases	ALPP, ALP, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, ALPI, IAP
External IDs	OMIM: 171800; MGI: 1924018; HomoloGene: 122414; GeneCards: ALPP; OMA:ALPP - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	232,382,889 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	87,029,328 bp
RNA expression pattern
	Top expressed in
	placenta; ; testicle; ; right uterine tube; ; upper lobe of left lung; ; right lung; ; lower lobe of lung; ; canal of the cervix; ; ectocervix; ; left ovary; ; muscle tissue;
	Top expressed in
	duodenum; ; epithelium of small intestine; ; jejunum; ; ileum; ; migratory enteric neural crest cell; ; sexually immature organism; ; stomach; ; lumbar subsegment of spinal cord; ; large intestine; ; colon;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	alkaline phosphatase activity; phosphatase activity; zinc ion binding; protein binding; hydrolase activity; catalytic activity; magnesium ion binding; metal ion binding;
Cellular component	integral component of membrane; anchored component of membrane; cell surface; membrane; plasma membrane;
Biological process	metabolism; dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	250
	76768
	ENSG00000163283
	ENSMUSG00000079440
	P05187
	F8VPQ6
	NM_001632
	NM_001081082
	NP_001623
	NP_001074551
	Wikidata
View/Edit Human	View/Edit Mouse

Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene.