AMP deaminase 2

AMPD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4NO3, 4NO5
Identifiers
Aliases	AMPD2, PCH9, SPG63, adenosine monophosphate deaminase 2
External IDs	OMIM: 102771; MGI: 88016; HomoloGene: 2979; GeneCards: AMPD2; OMA:AMPD2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	109,632,051 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	107,993,967 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; granulocyte; ; nucleus accumbens; ; pancreatic ductal cell; ; stromal cell of endometrium; ; right frontal lobe; ; monocyte; ; putamen; ; caudate nucleus; ; blood;
	Top expressed in
	fossa; ; arcuate nucleus; ; ventromedial nucleus; ; condyle; ; mammillary body; ; motor neuron; ; internal carotid artery; ; Rostral migratory stream; ; external carotid artery; ; lateral hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hydrolase activity; metal ion binding; deaminase activity; protein binding; AMP deaminase activity;
Cellular component	cellular component; cytosol;
Biological process	purine ribonucleoside monophosphate biosynthetic process; IMP salvage; cyclic purine nucleotide metabolic process; nucleotide metabolic process; purine-containing compound salvage; IMP biosynthetic process; energy homeostasis; AMP metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	271
	109674
	ENSG00000116337
	ENSMUSG00000027889
	Q01433
	Q9DBT5
NM_001257360; NM_001257361; NM_001308170; NM_004037; NM_139156;
	NM_203404; NM_001368809
	NM_001289719; NM_001289720; NM_028779; NM_001346665
NP_001244289; NP_001244290; NP_001295099; NP_004028; NP_631895;
	NP_001355738
	NP_001276648; NP_001276649; NP_001333594; NP_083055
	Wikidata
View/Edit Human	View/Edit Mouse

AMP deaminase 2 is an enzyme that in humans is encoded by the AMPD2 gene.

High AMPD2 expression levels correlate with poor patient outcome and a proliferative tumor phenotype in undifferentiated pleomorphic sarcoma (UPS).