ANGPTL3

ANGPTL3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	6EUA
Identifiers
Aliases	ANGPTL3, ANG-5, ANGPT5, ANL3, FHBL2, angiopoietin like 3
External IDs	OMIM: 604774; MGI: 1353627; HomoloGene: 8499; GeneCards: ANGPTL3; OMA:ANGPTL3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	62,606,313 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	98,934,348 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; kidney tubule; ; metanephric glomerulus; ; human kidney; ; testicle; ; gonad; ; buccal mucosa cell; ; Achilles tendon; ; epithelium of colon; ; stomach;
	Top expressed in
	left lobe of liver; ; fetal liver hematopoietic progenitor cell; ; right kidney; ; human fetus; ; tail of embryo; ; sexually immature organism; ; blastocyst; ; human kidney; ; embryo; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phospholipase inhibitor activity; enzyme inhibitor activity; integrin binding; growth factor activity; heparin binding;
Cellular component	Golgi apparatus; cell surface; early endosome; cell projection; lamellipodium; extracellular region; extracellular space;
Biological process	phospholipid homeostasis; positive regulation of cell migration; positive regulation of lipid catabolic process; lipid storage; cholesterol metabolic process; fatty acid metabolic process; positive regulation of angiogenesis; artery morphogenesis; lipid homeostasis; phospholipid catabolic process; integrin-mediated signaling pathway; negative regulation of lipoprotein lipase activity; response to hormone; phospholipid metabolic process; cholesterol homeostasis; acylglycerol homeostasis; cell-matrix adhesion; glycerol metabolic process; negative regulation of phospholipase activity; triglyceride homeostasis; signal transduction; lipid metabolism; cell adhesion; angiogenesis; regulation of lipoprotein lipase activity; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	27329
	30924
	ENSG00000132855
	ENSMUSG00000028553
	Q9Y5C1
	Q9R182
	NM_014495
	NM_013913
	NP_055310
	NP_038941
	Wikidata
View/Edit Human	View/Edit Mouse

Angiopoietin-like 3, also known as ANGPTL3, is a protein that in humans is encoded by the ANGPTL3 gene.