Angiopoietin-related protein 7

ANGPTL7
Identifiers
Aliases	ANGPTL7, AngX, CDT6, dJ647M16.1, angiopoietin like 7
External IDs	OMIM: 618517; MGI: 3605801; HomoloGene: 133923; GeneCards: ANGPTL7; OMA:ANGPTL7 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	11,195,981 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	148,584,917 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tibial nerve; ; sural nerve; ; tendon of biceps brachii; ; hair follicle; ; synovial joint; ; spinal ganglia; ; Descending thoracic aorta; ; testicle; ; ascending aorta;
	Top expressed in
	ankle; ; skin of external ear; ; lip; ; muscle of thigh; ; aortic valve; ; interventricular septum; ; medial head of gastrocnemius muscle; ; right kidney; ; uterus; ; sciatic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	extracellular region;
Biological process	response to oxidative stress;
	Sources:Amigo / QuickGO
Orthologs
	10218
	654812
	ENSG00000171819
	ENSMUSG00000028989
	O43827
	Q8R1Q3
	NM_021146
	NM_001039554
	NP_066969
	NP_001034643
	Wikidata
View/Edit Human	View/Edit Mouse

Angiopoietin-related protein 7 is a protein that in humans is encoded by the ANGPTL7 gene.

It is one of the 8 angiopoietin-like proteins.

Rare protein-altering variants in ANGPTL7, including p.Gln175His (0.007 minor allele frequency in Non-Finnish European population) and p.R220C (0.048 minor allele frequency in Finland), lower intraocular pressure and protect against glaucoma.