AP2M1

AP2M1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1H6E, 2JKT, 2JKR, 2VGL, 2BP5
Identifiers
Aliases	AP2M1, AP50, CLAPM1, mu2, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, MRD60
External IDs	OMIM: 601024; MGI: 1298405; HomoloGene: 3000; GeneCards: AP2M1; OMA:AP2M1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	184,184,214 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	20,363,659 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; prefrontal cortex; ; right hemisphere of cerebellum; ; right adrenal gland; ; right adrenal cortex; ; stromal cell of endometrium; ; left adrenal gland; ; left adrenal cortex; ; cingulate gyrus; ; ganglionic eminence;
	Top expressed in
	primary visual cortex; ; Cortex of frontal lobe; ; olfactory bulb; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; neural tube; ; Mesencephalon; ; hippocampus proper; ; Hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	lipid binding; clathrin adaptor activity; transporter activity; transmembrane transporter binding; protein binding; signal sequence binding; low-density lipoprotein particle receptor binding;
Cellular component	extracellular exosome; lysosomal membrane; AP-2 adaptor complex; endocytic vesicle membrane; cytosol; membrane; endolysosome membrane; clathrin adaptor complex; clathrin-coated pit; clathrin-coated endocytic vesicle membrane; plasma membrane; clathrin-coated endocytic vesicle;
Biological process	ephrin receptor signaling pathway; mitigation of host defenses by virus; clathrin-dependent endocytosis; negative regulation of protein localization to plasma membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; endocytosis; protein transport; vesicle-mediated transport; intracellular protein transport; Wnt signaling pathway, planar cell polarity pathway; microtubule-based movement; membrane organization; low-density lipoprotein particle receptor catabolic process; low-density lipoprotein particle clearance; transport; vesicle budding from membrane; receptor internalization; regulation of vesicle size;
	Sources:Amigo / QuickGO
Orthologs
	1173
	11773
	ENSG00000161203
	ENSMUSG00000022841
	Q96CW1
	P84091
	NM_004068; NM_001025205; NM_001311198
	NM_009679; NM_001302970
	NP_001020376; NP_001298127; NP_004059
	NP_001289899; NP_033809
	Wikidata
View/Edit Human	View/Edit Mouse

AP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene.