Apolipoprotein L1

APOL1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	7L6K, 7LF7, 7LFA, 7LFB, 7LFD
Identifiers
Aliases	APOL1, APO-L, APOL, APOL-I, FSGS4, apolipoprotein L1
External IDs	OMIM: 607254, 603743; GeneCards: APOL1; OMA:APOL1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	36,267,530 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; right lobe of liver; ; smooth muscle tissue; ; appendix; ; pericardium; ; upper lobe of left lung; ; apex of heart; ; decidua; ; nasal epithelium; ; right lung;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; chloride channel activity; lipid binding;
Cellular component	extracellular region; intrinsic component of membrane; blood microparticle; very-low-density lipoprotein particle; high-density lipoprotein particle; extracellular space; endoplasmic reticulum lumen;
Biological process	lipoprotein metabolic process; steroid metabolic process; lipid transport; innate immune response; cholesterol metabolic process; cytolysis; receptor-mediated endocytosis; killing of cells of other organism; lipid metabolism; post-translational protein modification; chloride transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	8542
	n/a
	ENSG00000100342
	n/a
	O14791
	n/a
NM_001136540; NM_001136541; NM_003661; NM_145343; NM_145344;
	NM_001362927
	n/a
	NP_001130012; NP_001130013; NP_003652; NP_663318; NP_001349856
	n/a
	Wikidata
View/Edit Human

Apolipoprotein L1 is a protein that in humans is encoded by the APOL1 gene. Two transcript variants encoding two different isoforms have been found for this gene.