ARF1

ARF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HUR, 1RE0, 1U81, 3O47, 4HMY, 1R8Q, 1RRG, 1RRF
Identifiers
Aliases	ARF1, ADP ribosylation factor 1, PVNH8
External IDs	OMIM: 103180; MGI: 99431; HomoloGene: 133930; GeneCards: ARF1; OMA:ARF1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,099,212 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,119,096 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; stromal cell of endometrium; ; cardiac muscle tissue of right atrium; ; beta cell; ; pituitary gland; ; anterior pituitary; ; corpus epididymis; ; right lung; ; upper lobe of lung; ; upper lobe of left lung;
	Top expressed in
	zygote; ; dentate gyrus of hippocampal formation granule cell; ; yolk sac; ; ankle joint; ; tail of embryo; ; right kidney; ; primary visual cortex; ; granulocyte; ; superior frontal gyrus; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phospholipase D activator activity; nucleotide binding; GTP binding; magnesium ion binding; GTPase activity; GDP binding; protein binding; RNA binding; protein domain specific binding; protein heterodimerization activity;
Cellular component	extracellular exosome; late endosome; cytoplasm; synapse; trans-Golgi network; Golgi apparatus; cell junction; endomembrane system; peroxisomal membrane; cell leading edge; neuron projection; postsynaptic density; postsynaptic membrane; membrane; focal adhesion; intracellular anatomical structure; perinuclear region of cytoplasm; sarcomere; COPI-coated vesicle; cytosol; Golgi membrane; plasma membrane; protein-containing complex; glutamatergic synapse;
Biological process	positive regulation of endocytosis; positive regulation of protein secretion; very-low-density lipoprotein particle assembly; mitigation of host defenses by virus; positive regulation of calcium ion-dependent exocytosis; regulation of receptor internalization; synaptic vesicle budding; small GTPase mediated signal transduction; cellular copper ion homeostasis; long-term depression; antigen processing and presentation of exogenous peptide antigen via MHC class II; Golgi to transport vesicle transport; post-Golgi vesicle-mediated transport; actin filament organization; lysosomal membrane organization; positive regulation of ER to Golgi vesicle-mediated transport; dendritic spine organization; regulation of phospholipid metabolic process; regulation of Arp2/3 complex-mediated actin nucleation; positive regulation of late endosome to lysosome transport; protein transport; phosphatidylinositol biosynthetic process; positive regulation of sodium ion transmembrane transport; vesicle-mediated transport; positive regulation of catalytic activity; positive regulation of dendritic spine development; mitotic cleavage furrow ingression; interleukin-12-mediated signaling pathway; transport; intracellular protein transport; Golgi to plasma membrane transport; postsynaptic actin cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	375
	11840
	ENSG00000143761
	ENSMUSG00000048076
	P84077
	P84078
	NM_001658; NM_001024226; NM_001024227; NM_001024228
	NM_001130408; NM_007476
	NP_001019397; NP_001019398; NP_001019399; NP_001649
	NP_001123880; NP_031502
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene.