ARHGAP1

ARHGAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR
Identifiers
Aliases	ARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, Rho GTPase activating protein 1
External IDs	OMIM: 602732; MGI: 2445003; HomoloGene: 20909; GeneCards: ARHGAP1; OMA:ARHGAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	46,700,619 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	91,502,671 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; saphenous vein; ; epithelium of esophagus; ; parietal pleura; ; visceral pleura; ; amniotic fluid; ; urethra; ; decidua; ; tail of epididymis; ; vena cava;
	Top expressed in
	yolk sac; ; granulocyte; ; corneal stroma; ; lip; ; genital tubercle; ; tail of embryo; ; morula; ; morula; ; blastocyst; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; protein binding; GTPase activator activity; cadherin binding;
Cellular component	cytosol; extracellular exosome; cytoplasm; endosome membrane; perinuclear region of cytoplasm; sorting endosome; membrane; integral component of membrane;
Biological process	regulation of small GTPase mediated signal transduction; Rho protein signal transduction; signal transduction; positive regulation of GTPase activity; small GTPase mediated signal transduction; positive regulation of signal transduction; transferrin transport; iron ion import across cell outer membrane; negative regulation of endocytic recycling; endosomal transport;
	Sources:Amigo / QuickGO
Orthologs
	392
	228359
	ENSG00000175220
	ENSMUSG00000027247
	Q07960
	Q5FWK3
	NM_004308
	NM_001145902; NM_146124; NM_001359970
	NP_004299
	NP_001139374; NP_666236; NP_001346899
	Wikidata
View/Edit Human	View/Edit Mouse

Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARHGAP1 gene.