ARHGDIA

ARHGDIA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CC0, 1FSO, 1FST, 1FT0, 1FT3, 1HH4, 1KMT, 1QVY, 1RHO, 2BXW, 2JHS, 2JHT, 2JHU, 2JHV, 2JHW, 2JHX, 2JHY, 2JHZ, 2JI0, 2N80
Identifiers
Aliases	ARHGDIA, GDIA1, HEL-S-47e, NPHS8, RHOGDI, RHOGDI-1, Rho GDP dissociation inhibitor alpha
External IDs	OMIM: 601925; MGI: 2178103; HomoloGene: 908; GeneCards: ARHGDIA; OMA:ARHGDIA - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,871,378 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,472,450 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; epithelium of colon; ; mucosa of transverse colon; ; left uterine tube; ; upper lobe of left lung; ; right lung; ; ascending aorta; ; left coronary artery; ; tibial nerve; ; anterior pituitary;
	Top expressed in
	tail of embryo; ; yolk sac; ; genital tubercle; ; tibiofemoral joint; ; lip; ; lactiferous gland; ; entorhinal cortex; ; mesenteric lymph nodes; ; perirhinal cortex; ; molar;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	GTPase activator activity; Rho GDP-dissociation inhibitor activity; protein binding;
Cellular component	cytoplasm; cytosol; extracellular exosome; cytoskeleton; membrane;
Biological process	negative regulation of cell adhesion; regulation of actin cytoskeleton reorganization; negative regulation of apoptotic process; positive regulation of axonogenesis; positive regulation of GTPase activity; negative regulation of axonogenesis; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; semaphorin-plexin signaling pathway; regulation of catalytic activity; Rho protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	396
	192662
	ENSG00000141522
	ENSMUSG00000025132
	P52565
	Q99PT1
NM_001185077; NM_001185078; NM_001301240; NM_001301241; NM_001301242;
	NM_001301243; NM_004309
	NM_133796; NM_001363425
NP_001172006; NP_001172007; NP_001288169; NP_001288170; NP_001288171;
	NP_001288172; NP_004300
	NP_598557; NP_001350354
	Wikidata
View/Edit Human	View/Edit Mouse

Rho GDP-dissociation inhibitor 1 is a protein that in humans is encoded by the ARHGDIA gene.