ARHGEF3

ARHGEF3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Z0Q
Identifiers
Aliases	ARHGEF3, GEF3, STA3, XPLN, Rho guanine nucleotide exchange factor 3
External IDs	OMIM: 612115; MGI: 1918954; HomoloGene: 41329; GeneCards: ARHGEF3; OMA:ARHGEF3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	57,079,329 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	27,125,868 bp
RNA expression pattern
	Top expressed in
	glomerulus; ; metanephric glomerulus; ; endothelial cell; ; Epithelium of choroid plexus; ; Brodmann area 23; ; germinal epithelium; ; middle temporal gyrus; ; granulocyte; ; oral cavity; ; parietal pleura;
	Top expressed in
	granulocyte; ; lobe of cerebellum; ; pontine nuclei; ; cerebellar vermis; ; right lung; ; right lung lobe; ; subiculum; ; deep cerebellar nuclei; ; olfactory tubercle; ; lateral septal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; guanyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; cytosol; intracellular anatomical structure;
Biological process	regulation of Rho protein signal transduction; intracellular signal transduction; regulation of small GTPase mediated signal transduction; Rho protein signal transduction; positive regulation of apoptotic process; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	50650
	71704
	ENSG00000163947
	ENSMUSG00000021895
	Q9NR81
	Q91X46
NM_001128615; NM_001128616; NM_001289698; NM_019555; NM_001377407;
	NM_001377408; NM_001377409; NM_001377410; NM_001377411; NM_001377412; NM_001377413; NM_001377414; NM_001377415
	NM_001289686; NM_001289687; NM_001289688; NM_027871
NP_001122087; NP_001122088; NP_001276627; NP_062455; NP_001364336;
	NP_001364337; NP_001364338; NP_001364339; NP_001364340; NP_001364341; NP_001364342; NP_001364343; NP_001364344
	NP_001276615; NP_001276616; NP_001276617; NP_082147
	Wikidata
View/Edit Human	View/Edit Mouse

Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene.