ASAH2

ASAH2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WGK
Identifiers
Aliases	ASAH2, BCDase, HNAC1, LCDase, N-CDase, NCDase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2
External IDs	OMIM: 611202; MGI: 1859310; HomoloGene: 10310; GeneCards: ASAH2; OMA:ASAH2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	50,279,720 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	32,085,611 bp
RNA expression pattern
	Top expressed in
	duodenum; ; gonad; ; testicle; ; stromal cell of endometrium; ; islet of Langerhans; ; smooth muscle tissue; ; ganglionic eminence; ; muscle of thigh; ; tonsil; ; skeletal muscle tissue;
	Top expressed in
	epithelium of small intestine; ; intestinal villus; ; jejunum; ; lacrimal gland; ; duodenum; ; esophagus; ; parotid gland; ; Epithelium of choroid plexus; ; deep cerebellar nuclei; ; motor neuron;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; ceramidase activity; calcium ion binding; zinc ion binding; N-acylsphingosine amidohydrolase activity; metal ion binding;
Cellular component	integral component of membrane; plasma membrane; membrane; mitochondrion; extracellular region;
Biological process	lipid metabolism; sphingolipid metabolic process; apoptotic process; sphingosine metabolic process; ceramide metabolic process; response to organic substance; long-chain fatty acid biosynthetic process; sphingosine biosynthetic process; ceramide catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	56624
	54447
	ENSG00000188611
	ENSMUSG00000024887
	Q9NR71
	Q9JHE3
	NM_001143974; NM_019893
	NM_018830
	NP_001137446; NP_063946
	NP_061300
	Wikidata
View/Edit Human	View/Edit Mouse

Neutral ceramidase is an enzyme that in humans is encoded by the ASAH2 gene.