Astrotactin

Astrotactin-1, abbreviated ASTN1, is a glycoprotein expressed primarily in the central nervous system. ASTN1 and its counterpart ASTN2 are involved in regulation of adhesion during the radial migration of neurons in the developing CNS. Astrotactin is a neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts with expression is primarily located in the cells of cortical regions of the developing brain including; cerebrum, hippocampus, cerebellum, and olfactory bulb.

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