ATP-sensitive potassium channel

potassium inwardly-rectifying channel, subfamily J, member 8
Identifiers
SymbolKCNJ8
Alt. symbolsKir6.1
NCBI gene3764
HGNC6269
OMIM600935
RefSeqNM_004982
UniProtQ15842
Other data
LocusChr. 12 p12.1
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StructuresSwiss-model
DomainsInterPro
potassium inwardly-rectifying channel, subfamily J, member 11
Identifiers
SymbolKCNJ11
Alt. symbolsKir6.2
NCBI gene3767
HGNC6257
OMIM600937
RefSeqNM_000525
UniProtQ14654
Other data
LocusChr. 11 p15.1
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StructuresSwiss-model
DomainsInterPro
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Identifiers
SymbolABCC8
Alt. symbolsSUR1
NCBI gene6833
HGNC59
OMIM600509
RefSeqNM_000352
UniProtQ09428
Other data
LocusChr. 11 p15.1
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StructuresSwiss-model
DomainsInterPro
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Identifiers
SymbolABCC9
Alt. symbolsSUR2A, SUR2B
NCBI gene10060
HGNC60
OMIM601439
RefSeqNM_005691
UniProtO60706
Other data
LocusChr. 12 p12.1
Search for
StructuresSwiss-model
DomainsInterPro

An ATP-sensitive potassium channel (or KATP channel) is a type of potassium channel that is gated by intracellular nucleotides, ATP and ADP. ATP-sensitive potassium channels are composed of Kir6.x-type subunits and sulfonylurea receptor (SUR) subunits, along with additional components. KATP channels are widely distributed in plasma membranes; however some may also be found on subcellular membranes. These latter classes of KATP channels can be classified as being either sarcolemmal ("sarcKATP"), mitochondrial ("mitoKATP"), or nuclear ("nucKATP").

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