ATP6V0D2

ATP6V0D2
Identifiers
Aliases	ATP6V0D2, ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2, ATP6D2, VMA6, ATPase H+ transporting V0 subunit d2
External IDs	OMIM: 618072; MGI: 1924415; HomoloGene: 72090; GeneCards: ATP6V0D2; OMA:ATP6V0D2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	86,154,225 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	19,922,605 bp
RNA expression pattern
	Top expressed in
	human kidney; ; buccal mucosa cell; ; amniotic fluid; ; renal medulla; ; testicle; ; rectum; ; tibia; ; muscle of thigh; ; mucosa of transverse colon; ; skin of hip;
	Top expressed in
	lumbar spinal ganglion; ; submandibular gland; ; body of femur; ; parotid gland; ; decidua; ; right kidney; ; calvaria; ; human kidney; ; right lung; ; right lung lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; proton transmembrane transporter activity; P-type proton-exporting transporter activity; proton-transporting ATPase activity, rotational mechanism;
Cellular component	proton-transporting V-type ATPase, V0 domain; endosome; phagocytic vesicle membrane; membrane; apical plasma membrane; vacuolar proton-transporting V-type ATPase complex; endosome membrane; extracellular exosome; lysosomal membrane; early endosome; plasma membrane proton-transporting V-type ATPase complex;
Biological process	insulin receptor signaling pathway; transferrin transport; ion transport; ion transmembrane transport; regulation of macroautophagy; phagosome acidification; vacuolar transport; vacuolar acidification; transport;
	Sources:Amigo / QuickGO
Orthologs
	245972
	242341
	ENSG00000147614
	ENSMUSG00000028238
	Q8N8Y2
	Q80SY3
	NM_152565
	NM_175406
	NP_689778
	NP_780615
	Wikidata
View/Edit Human	View/Edit Mouse

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 is a protein in humans that is encoded by the ATP6V0D2 gene. It is part of proton pumps in the plasma membranes of osteoclasts and aids with extracellular acidification in bone resorption.