Ataxin-2

ATXN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3KTR
Identifiers
Aliases	ATXN2, ASL13, ATX2, SCA2, TNRC13, ataxin 2
External IDs	OMIM: 601517; MGI: 1277223; HomoloGene: 2234; GeneCards: ATXN2; OMA:ATXN2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	111,599,676 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	121,816,493 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; epithelium of colon; ; olfactory bulb; ; sural nerve; ; ventricular zone; ; gonad; ; right uterine tube; ; C1 segment; ; right hemisphere of cerebellum; ; right ovary;
	Top expressed in
	internal carotid artery; ; genital tubercle; ; tail of embryo; ; neural layer of retina; ; external carotid artery; ; Ileal epithelium; ; zygote; ; cumulus cell; ; secondary oocyte; ; Rostral migratory stream;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	epidermal growth factor receptor binding; protein C-terminus binding; protein binding; RNA binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; polysome; trans-Golgi network; Golgi apparatus; cytoplasmic stress granule; membrane; cytosol; ribonucleoprotein complex;
Biological process	regulation of cytoplasmic mRNA processing body assembly; stress granule assembly; RNA metabolic process; regulation of translation; P-body assembly; RNA transport; negative regulation of receptor internalization;
	Sources:Amigo / QuickGO
Orthologs
	6311
	20239
	ENSG00000204842
	ENSMUSG00000042605
	Q99700
	O70305
	NM_001310121; NM_001310123; NM_002973; NM_001372574
	NM_009125; NM_001359153
	NP_001297050; NP_001297052; NP_002964; NP_001359503
	NP_033151; NP_001346082
	Wikidata
View/Edit Human	View/Edit Mouse

Ataxin-2 is a protein that in humans is encoded by the ATXN2 gene. Mutations in ATXN2 cause spinocerebellar ataxia type 2 (SCA2).