AUP1

AUP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EKF
Identifiers
Aliases	AUP1, ancient ubiquitous protein 1, lipid droplet regulating VLDL assembly factor, AUP1 lipid droplet regulating VLDL assembly factor
External IDs	OMIM: 602434; MGI: 107789; HomoloGene: 7239; GeneCards: AUP1; OMA:AUP1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	74,529,760 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	83,034,789 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; body of pancreas; ; mucosa of transverse colon; ; body of stomach; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; tendon of biceps brachii; ; spleen; ; right lobe of liver; ; minor salivary glands;
	Top expressed in
	right kidney; ; granulocyte; ; muscle of thigh; ; proximal tubule; ; choroid plexus of fourth ventricle; ; yolk sac; ; neural layer of retina; ; lip; ; superior frontal gyrus; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin binding; ubiquitin-protein transferase activator activity; protein binding;
Cellular component	extracellular exosome; endoplasmic reticulum membrane; membrane; integral component of endoplasmic reticulum membrane; Hrd1p ubiquitin ligase ERAD-L complex; integral component of membrane; endoplasmic reticulum;
Biological process	retrograde protein transport, ER to cytosol; ubiquitin-dependent ERAD pathway; regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	550
	11993
	ENSG00000115307
	ENSMUSG00000068328
	Q9Y679
	P70295
	NM_181575
	NM_001025446; NM_001301649; NM_007517
	NP_853553
	NP_001288578; NP_031543
	Wikidata
View/Edit Human	View/Edit Mouse

Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene.