Acacetin

Acacetin
Names
	IUPAC name 5,7-Dihydroxy-4′-methoxyflavone
	Systematic IUPAC name 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
	Other names 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one; Linarigenin; Acacetine; Buddleoflavonol; Linarisenin; 4′-Methoxyapigenin; Apigenin 4′-methyl ether; 5,7-Dioxy-4′-methoxyflavone
Identifiers
CAS Number	480-44-4 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEBI	CHEBI:15335 ;
ChEMBL	ChEMBL243664 ;
ChemSpider	4444099 ;
ECHA InfoCard	100.006.867
PubChem CID	5280442;
UNII	KWI7J0A2CC ;
CompTox Dashboard (EPA)	DTXSID00197383 ;
	InChI InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-8,17-18H,1H3 Key: DANYIYRPLHHOCZ-UHFFFAOYSA-N ; InChI=1/C16H12O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-8,17-18H,1H3 Key: DANYIYRPLHHOCZ-UHFFFAOYAN;
	SMILES COC1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O; O=C\1c3c(O/C(=C/1)c2ccc(OC)cc2)cc(O)cc3O;
Properties
Chemical formula	C16H12O5
Molar mass	284.26 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Acacetin is a 4′-O-methylated flavone of the parent compound apigenin, found in Robinia pseudoacacia (black locust), Turnera diffusa (damiana), Betula pendula (silver birch), and in the fern Asplenium normale.

In plant synthesis the enzyme apigenin 4′-O-methyltransferase uses S-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce S-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin).

It shows moderate aromatase inhibition.