Aceperone

Aceperone
Clinical data
Other names	Acetabuton; R 3248
ATC code	none;
Identifiers
	IUPAC name N-({1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-phenyl-4-piperidinyl}methyl)acetamide;
CAS Number	807-31-8;
PubChem CID	13122;
ChemSpider	12570;
UNII	S69KXZ59AB;
ChEMBL	ChEMBL136298;
CompTox Dashboard (EPA)	DTXSID30230510 ;
Chemical and physical data
Formula	C24H29FN2O2
Molar mass	396.506 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	97 to 100 °C (207 to 212 °F)
	SMILES Fc1ccc(cc1)C(=O)CCCN3CCC(c2ccccc2)(CC3)CNC(=O)C;
	InChI InChI=1S/C24H29FN2O2/c1-19(28)26-18-24(21-6-3-2-4-7-21)13-16-27(17-14-24)15-5-8-23(29)20-9-11-22(25)12-10-20/h2-4,6-7,9-12H,5,8,13-18H2,1H3,(H,26,28); Key:VDGZERMDPAAZEJ-UHFFFAOYSA-N;

Aceperone is a neuroleptic drug of the butyrophenone class. It is an α-noradrenergic blocking drug developed by Janssen Pharmaceutica in the 1960s.

Aceperone has been used as a tool in the study of the biochemical basis of learning. Although aceperone does not block learning per se, it blocks access to an attentional mechanism by which animals ‘tune in’ to the relevant visual dimension when learning a visual discrimination task at doses below those that affect general behaviour.