Alcoholic liver disease

Alcoholic liver disease
Other namesAlcohol-related liver disease
Microscopy of liver showing fatty change, cell necrosis, Mallory bodies
SpecialtyGastroenterology

Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis.

It is the major cause of liver disease in Western countries, and is the leading cause of death from excessive drinking. Although steatosis (fatty liver disease) will develop in any individual who consumes a large quantity of alcoholic beverages over a long period of time, this process is transient and reversible. More than 90% of all heavy drinkers develop fatty liver whilst about 25% develop the more severe alcoholic hepatitis, and 15% liver cirrhosis.

For patients with chronic hepatitis B, a strict adherence to abstinence from alcohol is highly recommended.