American Dad! season 10

The tenth season of the animated television series American Dad! originally aired on Fox from September 29, 2013, to May 18, 2014, and consisted of twenty episodes. Created by Seth MacFarlane, Matt Weitzman, and Mike Barker, the series continues to focus on the misadventures of the eccentric upper middle class Smith family in a fictionalized version of Langley, Virginia. A subplot occurring simultaneously throughout the season follows Jeff, Hayley's boyfriend, as he is sent to space in a previous episode. Season ten was the final full season to air on Fox, as the next is a mini-season only featuring three unaired episodes that Fox spontaneously aired.

On August 2, 2013, it was first announced that Mariah Carey would guest voice-star as a redneck character in the episode "Kung Pao Turkey". The heavily publicized episode aired on November 24, 2013. Also, the Christmas episode "Minstrel Krampus", which would have aired during the previous season but was delayed due to the Sandy Hook Elementary School shooting, aired on December 15, 2013.

The show was initially airing in its usual timeslot of 9:30 PM Eastern. Beginning on March 16 and continuing for the rest of the season, American Dad! moved to 7:30 PM Eastern; the move came as a result of the addition of Cosmos: A Spacetime Odyssey to the network's lineup.

Guest voice actors for the season include Zooey Deschanel, Danny Glover, Chloë Grace Moretz, Mark Cuban, Olivia Wilde, Sinbad, Josh Groban, Alan Thicke, Robin Thicke, Gillian Jacobs, Terry Crews, Gary Busey, Mae Whitman, Pete Holmes, Diego Luna, Patrick Stewart, Alison Brie and Nancy Cartwright as Bart Simpson.