American Midwest Conference
| Formerly | Show-Me Conference (1986–1994) | 
|---|---|
| Association | NAIA | 
| Founded | 1986 | 
| Commissioner | Will Wolper | 
| Sports fielded | 
 | 
| No. of teams | 12 (10 in 2025) | 
| Headquarters | St. Louis, Missouri | 
| Region | Midwest and South | 
| Official website | amcsportsonline.com | 
| Locations | |
The American Midwest Conference (AMC) is a college athletic conference affiliated with the National Association of Intercollegiate Athletics (NAIA) with 12 member institutions located in Arkansas and Missouri in the United States.