Amfepramone

Amfepramone
Clinical data
Trade names	Tenuate, Tepanil, Nobesine, others
Other names	Diethylpropion, Diethylcathinone
AHFS/Drugs.com	Monograph
MedlinePlus	a682037
License data	US DailyMed: Diethylpropion;
Pregnancy; category	AU: B2;
Routes of; administration	By mouth
ATC code	A08AA03 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); BR: Class B2 (Anorectic drugs); CA: Schedule G (CDSA IV); DE: Prescription only (Anlage III for higher doses); UK: Class C; US: Schedule IV; EU: Rx-only;
Pharmacokinetic data
Elimination half-life	4–6 hours (metabolites)
Excretion	Urine (>75%)
Identifiers
	IUPAC name (RS)-2-diethylamino-1-phenylpropan-1-one;
CAS Number	90-84-6 ;
PubChem CID	7029;
IUPHAR/BPS	7161;
DrugBank	DB00937 ;
ChemSpider	6762 ;
UNII	Q94YYU22B8;
KEGG	D07444 ;
ChEBI	CHEBI:4530 ;
ChEMBL	ChEMBL1194666 ;
CompTox Dashboard (EPA)	DTXSID6022929 ;
ECHA InfoCard	100.001.836
Chemical and physical data
Formula	C13H19NO
Molar mass	205.301 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C(c1ccccc1)C(N(CC)CC)C;
	InChI InChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3 ; Key:XXEPPPIWZFICOJ-UHFFFAOYSA-N ;
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Amfepramone, also known as diethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. It is used in the short-term management of obesity, along with dietary and lifestyle changes. Amfepramone has a similar chemical structure to the antidepressant and smoking cessation aid bupropion (previously called amfebutamone), which has also been developed as a weight-loss medicine when in a combination product with naltrexone.