Amniotic fluid embolism
| Amniotic fluid embolism | |
|---|---|
| Intravascular squames are present in this example of amniotic fluid embolism. | |
| Specialty | Obstetrics | 
| Risk factors | Advanced maternal age, history of pre-eclampsia, uterine rupture, fetal distress | 
| Frequency | 1 in 20,000 births | 
An amniotic fluid embolism (AFE) is a life-threatening childbirth (obstetric) emergency in which amniotic fluid enters the blood stream of the mother, triggering a serious reaction which results in cardiorespiratory (heart and lung) collapse and massive bleeding (coagulopathy). The rate at which it occurs is 1 instance per 20,000 births and it comprises 10% of all maternal deaths.