Archaeosine

Archaeosine
Names
IUPAC name
7-Carbaguanosine-7-carboximidamide
Systematic IUPAC name
2-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
Other names
7-Formamidino-7-deazaguanosine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C12H16N6O5/c13-8(14)3-1-18(9-5(3)10(22)17-12(15)16-9)11-7(21)6(20)4(2-19)23-11/h1,4,6-7,11,19-21H,2H2,(H3,13,14)(H3,15,16,17,22)/t4-,6-,7-,11-/m1/s1
    Key: PEMQXWCOMFJRLS-RPKMEZRRSA-N
  • C1=C(C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N)C(=N)N
Properties
C12H16N6O5
Molar mass 324.297 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Archaeosine (G*) is a modified nucleoside found in the dihydrouracil loop at position 15 of tRNAs found in Archaea, and is thought to be important for the heat resistance of thermophilic archaea such as Thermococcus kodakarensis.

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