Aripiprazole lauroxil

Aripiprazole lauroxil
Clinical data
Trade names	Aristada, Aristada Initio
Other names	N-Lauroyloxymethylaripiprazole; ALKS-9070; ALKS-9072; RDC-3317; Dodecanoic acid-[7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester
AHFS/Drugs.com	Monograph
MedlinePlus	a615048
License data	US DailyMed: Aripiprazole lauroxil;
Pregnancy; category	AU: C;
Routes of; administration	Intramuscular
ATC code	None;
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name [7-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate;
CAS Number	1259305-29-7;
PubChem CID	49831411;
DrugBank	DB14185;
ChemSpider	28651973;
UNII	B786J7A343;
KEGG	D10364;
ChEBI	CHEBI:90930;
ChEMBL	ChEMBL2219425;
CompTox Dashboard (EPA)	DTXSID60154997 ;
ECHA InfoCard	100.261.570
Chemical and physical data
Formula	C36H51Cl2N3O4
Molar mass	660.72 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCCCCCCC(=O)OCN1C(=O)CCC2=C1C=C(C=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl;
	InChI InChI=1S/C36H51Cl2N3O4/c1-2-3-4-5-6-7-8-9-10-16-35(43)45-28-41-33-27-30(19-17-29(33)18-20-34(41)42)44-26-12-11-21-39-22-24-40(25-23-39)32-15-13-14-31(37)36(32)38/h13-15,17,19,27H,2-12,16,18,20-26,28H2,1H3; Key:DDINXHAORAAYAD-UHFFFAOYSA-N;

Aripiprazole lauroxil, sold under the brand name Aristada among others, is a long-acting injectable atypical antipsychotic that was developed by Alkermes. It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to eight weeks for the treatment of schizophrenia. Aripiprazole lauroxil was approved by the US Food and Drug Administration (FDA) in October 2015.