Deutetrabenazine

Deutetrabenazine
Clinical data
Trade names	Austedo
Other names	Tetrabenazine D6; SD809; SD-809
AHFS/Drugs.com	Monograph
MedlinePlus	a617022
License data	US DailyMed: Deutetrabenazine;
Pregnancy; category	AU: B3;
Routes of; administration	By mouth
ATC code	N07XX16 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); BR: Class C1 (Other controlled substances); US: ℞-only;
Identifiers
	IUPAC name (3R,11bR)-3-(2-Methylpropyl)-9,10-bis(trideuteriomethoxy)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one;
CAS Number	1392826-25-3;
PubChem CID	73437646;
DrugBank	DB12161;
ChemSpider	34222717;
UNII	P341G6W9NB;
KEGG	D10701;
Chemical and physical data
Formula	C19H21D6NO3
Molar mass	323.462 g·mol−1

Deutetrabenazine (trade name Austedo) is a vesicular monoamine transporter 2 inhibitor which is used for the treatment of chorea associated with Huntington's disease and tardive dyskinesia.

Chemically, deutetrabenazine is an isotopic isomer of tetrabenazine in which six hydrogen atoms have been replaced by deuterium atoms. The incorporation of deuterium slows the rate of drug metabolism, allowing less frequent dosing.