B4GALT7

B4GALT7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4IRP, 4IRQ
Identifiers
Aliases	B4GALT7, EDSP1, XGALT1, XGPT1, EDSSLA, beta-1,4-galactosyltransferase 7, EDSSPD1, XGPT
External IDs	OMIM: 604327; MGI: 2384987; HomoloGene: 5248; GeneCards: B4GALT7; OMA:B4GALT7 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	177,610,330 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,758,256 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; right adrenal gland; ; left adrenal gland; ; left adrenal cortex; ; right adrenal cortex; ; anterior pituitary; ; apex of heart; ; body of pancreas; ; stromal cell of endometrium; ; body of stomach;
	Top expressed in
	saccule; ; otic vesicle; ; otic placode; ; cumulus cell; ; renal corpuscle; ; medullary collecting duct; ; decidua; ; granulocyte; ; blood; ; internal carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; manganese ion binding; glycosyltransferase activity; metal ion binding; galactosyltransferase activity; protein binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; xylosylprotein 4-beta-galactosyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; membrane; Golgi membrane; Golgi cisterna membrane;
Biological process	glycosaminoglycan metabolic process; protein glycosylation; proteoglycan metabolic process; glycosaminoglycan biosynthetic process; protein N-linked glycosylation; negative regulation of fibroblast proliferation; supramolecular fiber organization; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	11285
	218271
	ENSG00000027847
	ENSMUSG00000021504
	Q9UBV7
	Q8R087
	NM_007255
	NM_146045; NM_001311137
	NP_009186
	NP_001298066; NP_666157
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,4-galactosyltransferase 7 also known as galactosyltransferase I is an enzyme that in humans is encoded by the B4GALT7 gene. Galactosyltransferase I catalyzes the synthesis of the glycosaminoglycan-protein linkage in proteoglycans. Proteoglycans in turn are structural components of the extracellular matrix that is found between cells in connective tissues.