BRISC and BRCA1-A complex member 2

BABAM2
Identifiers
Aliases	BABAM2, BRCC4, BRCC45, BRE, brain and reproductive organ-expressed (TNFRSF1A modulator), BRISC and BRCA1 A complex member 2
External IDs	OMIM: 610497; MGI: 1333875; HomoloGene: 3604; GeneCards: BABAM2; OMA:BABAM2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	28,338,901 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	32,242,306 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; left adrenal cortex; ; right adrenal cortex; ; gastrocnemius muscle; ; right auricle of heart; ; popliteal artery; ; tibial arteries; ; left ventricle; ; muscle of thigh; ; anterior pituitary;
	Top expressed in
	lens; ; transitional epithelium of urinary bladder; ; adrenal gland; ; ankle; ; brown adipose tissue; ; granulocyte; ; epithelium of lens; ; left lobe of liver; ; muscle of thigh; ; epithelium of stomach;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peroxisome targeting sequence binding; polyubiquitin modification-dependent protein binding; protein binding; tumor necrosis factor receptor binding;
Cellular component	nuclear ubiquitin ligase complex; nucleoplasm; nucleus; cytoplasm; cytosol; BRCA1-A complex; BRISC complex;
Biological process	response to ionizing radiation; positive regulation of DNA repair; cell division; protein K63-linked deubiquitination; cell cycle; double-strand break repair via nonhomologous end joining; signal transduction; apoptotic process; DNA repair; cellular response to DNA damage stimulus; double-strand break repair; protein deubiquitination; negative regulation of apoptotic process; mitotic G2 DNA damage checkpoint signaling; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	9577
	107976
	ENSG00000158019
	ENSMUSG00000052139
	Q9NXR7
	Q8K3W0
NM_001261840; NM_001329112; NM_001329113; NM_001329114; NM_001329115;
	NM_004899; NM_199191; NM_199192; NM_199193; NM_199194
	NM_144541; NM_181279; NM_181280; NM_181281; NM_181282
NP_001248769; NP_001316041; NP_001316042; NP_001316043; NP_001316044;
	NP_004890; NP_954661; NP_954662; NP_954663; NP_954664
	NP_653124; NP_851796; NP_851797; NP_851798; NP_851799
	Wikidata
View/Edit Human	View/Edit Mouse

BRISC and BRCA1-A complex member 2 is a protein in humans encoded by the BABAM2 gene.