BAG4

BAG4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1M62, 1M7K
Identifiers
Aliases	BAG4, BAG-4, SODD, BCL2 associated athanogene 4, BAG cochaperone 4
External IDs	OMIM: 603884; MGI: 1914634; HomoloGene: 31270; GeneCards: BAG4; OMA:BAG4 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	38,213,301 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	26,275,315 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; lateral nuclear group of thalamus; ; postcentral gyrus; ; germinal epithelium; ; Pons; ; entorhinal cortex; ; epithelium of nasopharynx; ; superior frontal gyrus; ; pars compacta; ; cerebellar vermis;
	Top expressed in
	primary oocyte; ; dentate gyrus of hippocampal formation granule cell; ; zygote; ; Region I of hippocampus proper; ; seminiferous tubule; ; visual cortex; ; lateral septal nucleus; ; retinal pigment epithelium; ; ventromedial nucleus; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chaperone binding; ubiquitin protein ligase binding; protein binding; adenyl-nucleotide exchange factor activity; RNA binding;
Cellular component	cytoplasm; plasma membrane; cytosol; nucleus;
Biological process	positive regulation of peptidyl-serine phosphorylation; positive regulation of fibroblast migration; negative regulation of apoptotic process; negative regulation of protein targeting to mitochondrion; cellular response to epidermal growth factor stimulus; positive regulation of protein kinase B signaling; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; positive regulation of stress fiber assembly; protein folding; tumor necrosis factor-mediated signaling pathway; positive regulation of actin filament polymerization; protein localization to plasma membrane; ruffle assembly; positive regulation of cell adhesion; regulation of cellular response to heat; cellular response to tumor necrosis factor; negative regulation of mRNA modification; protein heterooligomerization;
	Sources:Amigo / QuickGO
Orthologs
	9530
	67384
	ENSG00000156735
	ENSMUSG00000037316
	O95429
	Q8CI61
	NM_004874; NM_001204878
	NM_026121
	NP_001191807; NP_004865
	NP_080397
	Wikidata
View/Edit Human	View/Edit Mouse

BAG family molecular chaperone regulator 4 is a protein that in humans is encoded by the BAG4 gene.