BCAS3

BCAS3
Identifiers
Aliases	BCAS3, GAOB1, MAAB, breast carcinoma amplified sequence 3, microtubule associated cell migration factor, BCAS3 microtubule associated cell migration factor, PHAF2, HEMARS
External IDs	OMIM: 607470; MGI: 2385848; HomoloGene: 9778; GeneCards: BCAS3; OMA:BCAS3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	61,392,838 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	85,826,058 bp
RNA expression pattern
	Top expressed in
	epithelium of colon; ; sural nerve; ; right uterine tube; ; bone marrow cells; ; Achilles tendon; ; prefrontal cortex; ; testicle; ; olfactory zone of nasal mucosa; ; right coronary artery; ; popliteal artery;
	Top expressed in
	seminal vesicula; ; morula; ; muscle of thigh; ; neural layer of retina; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; genital tubercle; ; blastocyst; ; lip; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	histone binding; chromatin binding; acetyltransferase activator activity; beta-tubulin binding; histone acetyltransferase binding; transcription factor binding; protein binding;
Cellular component	intermediate filament cytoskeleton; nucleolus; cell periphery; cell leading edge; cytoplasmic microtubule; cytoskeleton; nucleus; cytoplasm;
Biological process	angiogenesis; cellular response to estrogen stimulus; positive regulation of endothelial cell migration; positive regulation of GTPase activity; positive regulation of intracellular protein transport; transcription, DNA-templated; positive regulation of actin cytoskeleton reorganization; microtubule organizing center organization; negative regulation of focal adhesion assembly; response to starvation; activation of GTPase activity; Golgi organization; regulation of establishment of cell polarity; tube formation; regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; negative regulation of GTPase activity; positive regulation of catalytic activity; positive regulation of filopodium assembly; vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	54828
	192197
	ENSG00000141376
	ENSMUSG00000059439
	Q9H6U6
	Q8CCN5
NM_001099432; NM_017679; NM_001320470; NM_001330413; NM_001330414;
	NM_001353144; NM_001353145; NM_001353146
	NM_001166642; NM_001166643; NM_138681
NP_001092902; NP_001307399; NP_001317342; NP_001317343; NP_060149;
	NP_001340073; NP_001340074; NP_001340075
	NP_001160114; NP_001160115; NP_619622
	Wikidata
View/Edit Human	View/Edit Mouse

Breast carcinoma amplified sequence 3, also known as BCAS3, is a protein which in humans is encoded by the BCAS3 gene. BCAS3 is a gene that is amplified and overexpressed in breast cancer cells.