Bcl-2-interacting killer

BIK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IPE
Identifiers
Aliases	BIK, BIP1, BP4, NBK, BCL2 interacting killer
External IDs	OMIM: 603392; MGI: 1206591; HomoloGene: 924; GeneCards: BIK; OMA:BIK - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	43,129,712 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,428,835 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; olfactory zone of nasal mucosa; ; palpebral conjunctiva; ; mucosa of transverse colon; ; gonad; ; epithelium of bronchus; ; bronchial epithelial cell; ; mucosa of sigmoid colon; ; minor salivary glands; ; mucosa of paranasal sinus;
	Top expressed in
	right kidney; ; lumbar spinal ganglion; ; proximal tubule; ; embryo; ; conjunctival fornix; ; primary oocyte; ; zygote; ; transitional epithelium of urinary bladder; ; right lung lobe; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; BH domain binding; protein heterodimerization activity;
Cellular component	integral component of membrane; endomembrane system; mitochondrial membranes; mitochondrion; membrane;
Biological process	regulation of apoptotic process; positive regulation of protein homooligomerization; positive regulation of release of cytochrome c from mitochondria; apoptotic process; male gonad development; apoptotic mitochondrial changes;
	Sources:Amigo / QuickGO
Orthologs
	638
	12124
	ENSG00000100290
	ENSMUSG00000016758
	Q13323
	O70337
	NM_001197
	NM_007546
	NP_001188; NP_001188.1
	NP_031572
	Wikidata
View/Edit Human	View/Edit Mouse

Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene.