BLUF domain
| BLUF | |||||||||
|---|---|---|---|---|---|---|---|---|---|
structure of a cyanobacterial bluf protein, tll0078 | |||||||||
| Identifiers | |||||||||
| Symbol | BLUF | ||||||||
| Pfam | PF04940 | ||||||||
| InterPro | IPR007024 | ||||||||
| |||||||||
In molecular biology, the BLUF domain (sensors of blue-light using FAD) is a FAD-binding protein domain. They are present in various proteins, primarily from bacteria, for example a BLUF domain is found at the N-terminus of the AppA protein from Rhodobacter sphaeroides. The BLUF domain is involved in sensing blue-light (and possibly redox) using FAD and is similar to the flavin-binding PAS domains and cryptochromes. The predicted secondary structure reveals that the BLUF domain has a novel FAD-binding fold.