Bone morphogenetic protein 15

BMP15
Identifiers
Aliases	BMP15, GDF9B, ODG2, POF4, bone morphogenetic protein 15
External IDs	OMIM: 300247; MGI: 1316745; HomoloGene: 3977; GeneCards: BMP15; OMA:BMP15 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	50,916,641 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	6,232,775 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; fallopian tube; ; ventricular zone; ; olfactory zone of nasal mucosa; ; ovary; ; left ovary;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; lumbar spinal ganglion; ; egg cell; ; embryo; ; morula; ; cumulus cell; ; seminal vesicula; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transforming growth factor beta receptor binding; growth factor activity; cytokine activity;
Cellular component	cytoplasm; extracellular region; extracellular space; endoplasmic reticulum lumen;
Biological process	ovarian follicle development; female gamete generation; positive regulation of pathway-restricted SMAD protein phosphorylation; BMP signaling pathway; regulation of apoptotic process; regulation of MAPK cascade; cell development; granulosa cell development; SMAD protein signal transduction; positive regulation of transcription, DNA-templated; post-translational protein modification; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	9210
	12155
	ENSG00000130385
	ENSMUSG00000023279
	O95972
	Q9Z0L4
	NM_005448
	NM_009757
	NP_005439
	NP_033887
	Wikidata
View/Edit Human	View/Edit Mouse

Bone morphogenetic protein 15 (BMP-15) is a protein that in humans is encoded by the BMP15 gene. It is involved in folliculogenesis, the process in which primordial follicles develop into pre-ovulatory follicles.