Zinc finger protein basonuclin-2

BNC2
Identifiers
Aliases	BNC2, BSN2, basonuclin 2, LUTO
External IDs	OMIM: 608669; MGI: 2443805; HomoloGene: 18243; GeneCards: BNC2; OMA:BNC2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	16,870,843 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	84,593,512 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; sural nerve; ; parietal pleura; ; epithelium of colon; ; hair follicle; ; buccal mucosa cell; ; left ovary; ; right ovary; ; myometrium; ; testicle;
	Top expressed in
	zygote; ; oocyte; ; secondary oocyte; ; primary oocyte; ; Gonadal ridge; ; vas deferens; ; sciatic nerve; ; lumbar spinal ganglion; ; hand; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; DNA binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; plasma membrane; cytosol;
Biological process	tongue development; endochondral bone growth; regulation of transcription, DNA-templated; mesenchyme development; roof of mouth development; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	54796
	242509
	ENSG00000173068
	ENSMUSG00000028487
	Q6ZN30; Q06HC2
	Q8BMQ3
	NM_017637; NM_001317939; NM_001317940
	NM_172870; NM_001369081; NM_001369082; NM_001369083; NM_001369084
	NP_001304868; NP_001304869; NP_060107
	NP_766458; NP_001356010; NP_001356011; NP_001356012; NP_001356013
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein basonuclin-2 is a protein that in humans is encoded by the BNC2 gene. BNC2 has recently been shown to influence skin pigmentation levels in Europeans. Genomic region spanning the BNC2 gene has 60% Neanderthal DNA sequence.