BPIFB1

BPIFB1
Identifiers
Aliases	BPIFB1, C20orf114, LPLUNC1, BPI fold containing family B member 1
External IDs	MGI: 2137431; HomoloGene: 50047; GeneCards: BPIFB1; OMA:BPIFB1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	33,309,871 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	154,062,289 bp
RNA expression pattern
	Top expressed in
	bronchus; ; bronchial epithelial cell; ; trachea; ; olfactory zone of nasal mucosa; ; nasal epithelium; ; mucosa of paranasal sinus; ; parotid gland; ; epithelium of nasopharynx; ; minor salivary glands; ; mucosa of pharynx;
	Top expressed in
	epithelium of stomach; ; mucous cell of stomach; ; trachea; ; right lung; ; right lung lobe; ; olfactory epithelium; ; lumbar spinal ganglion; ; external carotid artery; ; sexually immature organism; ; internal carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	lipid binding; molecular function;
Cellular component	extracellular exosome; extracellular region; extracellular space;
Biological process	innate immune response in mucosa; innate immune response; negative regulation of toll-like receptor 4 signaling pathway; immune system process; antimicrobial humoral response;
	Sources:Amigo / QuickGO
Orthologs
	92747
	228801
	ENSG00000125999
	ENSMUSG00000027485
	Q8TDL5
	Q61114
	NM_033197
	NM_001012392; NM_153418
	NP_149974
	NP_001012392; NP_700467
	Wikidata
View/Edit Human	View/Edit Mouse

BPI fold-containing family B member 1 (BPIFB1) is a protein that in humans is encoded by the BPIFB1 gene. BPIFB1 is a secreted protein, expressed at very high levels in mucosa of the airways (respiratory and olfactory epithelium) and salivary glands, and at moderate levels in the digestive tract (tongue, stomach, intestinal epithelium) and pancreas.