BRSK1

BRSK1
Identifiers
Aliases	BRSK1, hSAD1, BR serine/threonine kinase 1, SAD-B
External IDs	OMIM: 609235; MGI: 2685946; HomoloGene: 57169; GeneCards: BRSK1; OMA:BRSK1 - orthologs
EC number	2.7.11.26
Gene location (Human)
Chr.	Chromosome 19 (human)
End	55,312,562 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,718,996 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; Brodmann area 9; ; right hemisphere of cerebellum; ; prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex; ; ganglionic eminence; ; Amygdala; ; Hypothalamus; ; putamen;
	Top expressed in
	primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; prefrontal cortex; ; central gray substance of midbrain; ; cerebellar cortex; ; nucleus of stria terminalis; ; hippocampus proper; ; cingulate gyrus; ; piriform cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; metal ion binding; kinase activity; protein kinase binding; magnesium ion binding; protein serine/threonine kinase activity; ATP binding; tau-protein kinase activity; gamma-tubulin binding; tau protein binding;
Cellular component	synapse; nucleoplasm; microtubule organizing center; cytoskeleton; cell junction; cytoplasm; synaptic vesicle; centrosome; nucleus; presynaptic active zone; distal axon;
Biological process	response to ionizing radiation; neuron projection morphogenesis; intracellular signal transduction; phosphorylation; nervous system development; cell cycle; response to UV; cellular response to DNA damage stimulus; centrosome duplication; establishment of cell polarity; neurotransmitter secretion; axonogenesis; neuron differentiation; protein phosphorylation; mitotic G2 DNA damage checkpoint signaling; associative learning; regulation of neuron projection development; regulation of synaptic plasticity; regulation of axonogenesis; microtubule cytoskeleton organization involved in establishment of planar polarity; synaptic vesicle cycle; regulation of synaptic vesicle clustering;
	Sources:Amigo / QuickGO
Orthologs
	84446
	381979
	ENSG00000160469
	ENSMUSG00000035390
	Q8TDC3
	Q5RJI5
	NM_032430
	NM_001003920; NM_001168572
	NP_115806
	NP_001003920; NP_001162044
	Wikidata
View/Edit Human	View/Edit Mouse

BR serine/threonine kinase 1 is an enzyme that in humans is encoded by the BRSK1 gene.