BRSK2

BRSK2
Identifiers
Aliases	BRSK2, C11orf7, PEN11B, SAD1, SADA, STK29, BR serine/threonine kinase 2, SAD-A
External IDs	OMIM: 609236; MGI: 1923020; HomoloGene: 123829; GeneCards: BRSK2; OMA:BRSK2 - orthologs
EC number	2.7.11.26
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,462,689 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,557,984 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; body of pancreas; ; right frontal lobe; ; ganglionic eminence; ; anterior cingulate cortex; ; Brodmann area 9; ; prefrontal cortex; ; C1 segment; ; nucleus accumbens; ; Amygdala;
	Top expressed in
	visual cortex; ; primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; cerebellar cortex; ; prefrontal cortex; ; hippocampus proper; ; ganglionic eminence; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; ATPase binding; ATPase regulator activity; metal ion binding; kinase activity; protein kinase binding; magnesium ion binding; tau-protein kinase activity; protein serine/threonine kinase activity; ATP binding; tau protein binding;
Cellular component	centrosome; microtubule organizing center; perinuclear region of cytoplasm; cytoskeleton; nucleus; cytoplasm; endoplasmic reticulum; distal axon;
Biological process	actin cytoskeleton reorganization; neuron projection morphogenesis; ERAD pathway; phosphorylation; nervous system development; cell division; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; G2/M transition of mitotic cell cycle; peptidyl-serine phosphorylation; cell cycle; regulation of ATP-dependent activity; regulation of retrograde protein transport, ER to cytosol; exocytosis; apoptotic process; establishment of cell polarity; regulation of insulin secretion involved in cellular response to glucose stimulus; axonogenesis; protein phosphorylation; neuron differentiation; regulation of neuron projection development; intracellular signal transduction; regulation of axonogenesis; microtubule cytoskeleton organization involved in establishment of planar polarity; regulation of synaptic vesicle clustering;
	Sources:Amigo / QuickGO
Orthologs
	9024
	75770
	ENSG00000174672
	ENSMUSG00000053046
	Q8IWQ3
	Q69Z98
	NM_001256627; NM_001256629; NM_001256630; NM_001282218; NM_003957
	NM_001009929; NM_001009930; NM_001276763; NM_029426
	NP_001243556; NP_001243558; NP_001243559; NP_001269147; NP_003948
	NP_001009929; NP_001009930; NP_001263692; NP_083702
	Wikidata
View/Edit Human	View/Edit Mouse

BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene.