BSCL2

BSCL2
Identifiers
Aliases	BSCL2, GNG3LG, HMN5, PELD, SPG17, Berardinelli-Seip congenital lipodystrophy 2 (seipin), seipin lipid droplet biogenesis associated, BSCL2 lipid droplet biogenesis associated, seipin, HMN5C
External IDs	OMIM: 606158; MGI: 1298392; HomoloGene: 32032; GeneCards: BSCL2; OMA:BSCL2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	62,709,845 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	8,826,047 bp
RNA expression pattern
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; pituitary gland; ; anterior pituitary; ; right testis; ; Brodmann area 9; ; left testis; ; nucleus accumbens; ; caudate nucleus; ; Hypothalamus;
	Top expressed in
	tunica adventitia of aorta; ; seminiferous tubule; ; white adipose tissue; ; brown adipose tissue; ; subcutaneous adipose tissue; ; facial motor nucleus; ; motor neuron; ; fossa; ; paraventricular nucleus of hypothalamus; ; condyle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	integral component of membrane; integral component of endoplasmic reticulum membrane; endoplasmic reticulum; endoplasmic reticulum membrane; membrane;
Biological process	lipid catabolic process; lipid storage; negative regulation of lipid catabolic process; fat cell differentiation; lipid droplet organization; lipid metabolism; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	26580
	14705
	ENSG00000168000
	ENSMUSG00000071657
	Q96G97
	Q9Z2E9
	NM_001122955; NM_001130702; NM_032667; NM_001386027; NM_001386028
	NM_001136064; NM_001290823; NM_008144
	NP_001116427; NP_001124174; NP_116056
	NP_001129536; NP_001277752; NP_032170
	Wikidata
View/Edit Human	View/Edit Mouse

Seipin is a protein that in humans is encoded by the BSCL2 gene.