Butyrophilin, subfamily 1, member A1

BTN1A1
Identifiers
Aliases	BTN1A1, BT, BTN, BTN1, butyrophilin subfamily 1 member A1
External IDs	OMIM: 601610; MGI: 103118; HomoloGene: 1312; GeneCards: BTN1A1; OMA:BTN1A1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	26,510,425 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	23,650,071 bp
RNA expression pattern
	Top expressed in
	gonad; ; lymph node; ; appendix; ; tonsil; ; spleen; ; blood; ; granulocyte; ; urinary bladder; ; C1 segment; ; duodenum;
	Top expressed in
	lactiferous gland; ; ascending aorta; ; female urethra; ; aortic valve; ; embryo; ; atrioventricular junction; ; endocardial cushion; ; Paneth cell; ; gastrula; ; atrioventricular valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; signaling receptor activity;
Cellular component	integral component of membrane; extracellular region; integral component of plasma membrane; membrane; extracellular space; plasma membrane; external side of plasma membrane;
Biological process	regulation of immune response; T cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	696
	12231
	ENSG00000124557
	ENSMUSG00000000706
	Q13410
	Q62556
	NM_001732
	NM_013483
	NP_001723
	NP_038511
	Wikidata
View/Edit Human	View/Edit Mouse

Butyrophilin subfamily 1 member A1 is a protein that in humans is encoded by the BTN1A1 gene.

Butyrophilin (BTN) is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families